Rapid developments in network-based application demand a special attention to protect the confidentiality of data. Cryptographic algorithms play a lead role in ensuring confidentiality assisted by key generation architecture. Keys have a fair role in modern cryptography, which can be generated through random number generators. To meet the real-time requirements, cryptographic primitives can be developed on reconfigurable hardware such as Field Programmable Gate Arrays (FPGAs). This work focuses on the development of Pseudo Random Number Generation (PRNG) architecture using Cellular Automata (CA) on Altera Cyclone II EP2C20F484C7 FPGA at an operating frequency of 50 MHz. Significantly, CA based random sequences were generated based on five rules namely R30, R90, R105, R150 and R165. The randomness of the proposed Pseudo Random Number Generator (PRNG) has been confirmed using entropy and NIST 800 – 22 tests. The proposed design has consumed only 461 logic elements which are 3% of total logic elements of target FPGA and also achieves a throughput of 51.603 Mbps for 128-bit PRNG with a power dissipation of 72.26 mW.