To determine phytochemistry, ovicidal and repellent activity of Sesamum indicum extracts against Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus. Phytochemistry properties of flavonoids, tannins, terpenoids, tri-terpenoids, anthraquinones, protein, phenol and phytosteroids present in the methanol extract of S. indicum. The ovicidal activity was firm against A. aegypti, An. stephensi and Cx. quinquefasciatus to varied concentrations starting from 50-300 ppm underneath the laboratory conditions. The repellent activity of S. indicum tested at concentrations of 5.0 mg/cm2 was evaluated in an exceedingly net cage (45cm × 30cm × 45cm) containing 100 blood starved female mosquitoes of A. aegypti, An. stephensi and Cx. quinquefasciatus using the protocol of WHO (2009). Phytochemical screen of methanol extracts of S. indicum plant contain flavonoids, saponins, tannins, terpenoids, tri-terpenoids, anthraquinones, phenol, protein and phytosteroids. Similarly, the methanol extract of S. indicum was found to be most effective against Cx. quinquefasciatus. For methanol extract exerted 250 and 300 ppm, respectively. The repellent activity of methanol extract of S. indicum was most effective and maximum activity was observed at 5.0 mg/cm2 concentration provided 100% protection up to 120, 150 and 180 minutes against Cx. quinquefasciatus. In this study was undertaken to assess the phytochemistry, ovicidal and repellent potential of methanol extracts from the S. indicum against Cx. quinquefasciatus.
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