Primary trifluoroborate-iminiums enable facile access to chiral α-aminoboronic acids via Ru-catalyzed asymmetric hydrogenation and simple hydrolysis of the trifluoroborate moiety
- Resource Type
- Authors
- Andrej Šterman; Izidor Sosič; Zdenko Časar
- Source
- Chemical Science. 13:2946-2953
- Subject
- General Chemistry
- Language
- ISSN
- 2041-6539
2041-6520
Starting with potassium acyltrifluoroborates (KATs), N-unprotected chiral α-aminoboronic acids are prepared in three simple steps without chromatography. This facile methodology will tap the broad potential of these valuable compounds.