Thrombotic Microangiopathy Causing Acute Kidney Injury in a COVID-19 Patient
- Resource Type
- Authors
- Srinivasa Polumuru; Amitabh Kulkarni; Prashant Nasa; Aanchal Singh
- Source
- Indian Journal of Nephrology
- Subject
- medicine.medical_specialty
Thrombotic microangiopathy
Coronavirus disease 2019 (COVID-19)
business.industry
urogenital system
Acute kidney injury
COVID-19
Case Report
medicine.disease
urologic and male genital diseases
Gastroenterology
female genital diseases and pregnancy complications
complement mediated microangiopathy
AKI
Nephrology
Internal medicine
medicine
TMA
business
- Language
- English
- ISSN
- 1998-3662
0971-4065
Acute Kidney Injury (AKI) in COVID-19 patients is common and independently associated with higher mortality. The pathophysiology of AKI is multifactorial and may be either direct viral trophism or immune mediated injury and hypercoagulability. This case highlights AKI in a young female with severe COVID-19 due to complement-3 mediated thrombotic microangiopathy with pre-existing chronic kidney disease likely because of IgA nephropathy.