Changes in cholesteryl ester transfer protein concentration during normal gestation
- Resource Type
- Authors
- Junjun Wang; Guohong Wang; Chunni Zhang; Xiaozhuan Liu; Qi Liu; Yiyi Zhuang; Daning Chen
- Source
- European Journal of Lipid Science and Technology. 108:730-734
- Subject
- medicine.medical_specialty
Pregnancy
biology
medicine.drug_class
Chemistry
Endogeny
General Chemistry
Normal pregnancy
Third trimester
medicine.disease
Industrial and Manufacturing Engineering
carbohydrates (lipids)
First trimester
Endocrinology
Estrogen
Internal medicine
Cholesterylester transfer protein
medicine
biology.protein
Gestation
lipids (amino acids, peptides, and proteins)
Food Science
Biotechnology
- Language
- ISSN
- 1438-9312
1438-7697
Background: It has been shown that endogenous estrogen may affect the concentration of cholesteryl ester transfer protein (CETP) and that the gestation in women is accompanied by increased levels of endogenous estrogen. Objectives: To examine the changes in CETP concentration and to investigate the relationship between CETP and estrogen levels during normal pregnancy. Methods: Serum concentrations of CETP, estrogen and lipid traits were determined from 296 healthy women at different times during gestation. Results: Pregnant women exhibited a significant elevation in the concentration of CETP as compared with non-pregnant women (3.11 ± 1.51 mg/L vs. 2.64 ± 1.25 mg/L, p