3-(4-Phosphoryl-4-methyl-2-oxopentyl)-3-hydroxyindolin-2-ones, the first phosphorus analogues of natural convolutamydines
- Resource Type
- Authors
- Robert R. Fayzullin; Andrei V. Bogdanov; D. A. Tatarinov; Victoria Osipova; Vladimir F. Mironov
- Source
- Mendeleev Communications. 28:292-294
- Subject
- 010405 organic chemistry
Chemistry
organic chemicals
Phosphorus
Isatin
chemistry.chemical_element
General Chemistry
Reversible process
010402 general chemistry
01 natural sciences
0104 chemical sciences
chemistry.chemical_compound
Organic chemistry
Aldol condensation
- Language
- ISSN
- 0959-9436
The first examples of phosphorus-containing analogues of natural alkaloids, convolutamydines, have been obtained by aldol condensation of 4-[dialkyl(diphenyl)phosphoryl]-4-methylpentan-2-one with isatin. An unusually facile reversible process of dehydration–hydration of these phosphorus-containing hydroxy indoles has been discovered.