NEURODEM: assessment of the iatrogenic alert indicator for nursing home patients with Alzheimer's or Alzheimer-like disease
- Resource Type
- Authors
- Samir Henni; Gwennaelle Feinard; Sylvie Piessard; Laure de Decker; Gwennäelle Veyrac; Gilles Berrut; Jean-Francois Pujol; Anne Sonnic; Florence Delamarre Damier
- Source
- Aging clinical and experimental research. 28(5)
- Subject
- Male
Aging
medicine.medical_specialty
Iatrogenic Disease
Disease
Tardive dyskinesia
03 medical and health sciences
0302 clinical medicine
Alzheimer Disease
medicine
Dementia
Humans
030212 general & internal medicine
Psychiatry
Aged
Aged, 80 and over
030214 geriatrics
business.industry
Parkinsonism
Cognition
medicine.disease
nervous system diseases
Nursing Homes
Increased risk
Female
Geriatrics and Gerontology
Alzheimer's disease
Nursing homes
business
Antipsychotic Agents
- Language
- ISSN
- 1720-8319
Neuroleptics are known to induce Parkinsonism, tardive dyskinesia and their long-term use was associated with increased risk of hip fractures and impaired cognitive function and even death.The primary objective of Neurodem study was to determine the IAI of patients with Alzheimer's disease in French NH.1022 patients were enrolled. The IAI was 24.8 %. Multivariate logistic analysis showed that having a severe form of dementia, resident without MMS evaluation the last 12 months and having a prescription for an anxiolytic drug were associated with a higher risk of having a prescription for an antipsychotic drug.The results from our study show that the percentage of patients receiving an antipsychotic drug (24.8 %) was higher than the national average (18 %). Effective educational activities about appropriate use of antipsychotic drugs in patients with Alzheimer's disease are needed.