Continuous monitoring of cerebral oxygen saturation in elderly patients undergoing major abdominal surgery minimizes brain exposure to potential hypoxia
- Resource Type
- Authors
- Casati, Andrea; Fanelli, Guido; Pietropaoli, Paolo; Proietti, Rodolfo; Tufano, Rosalba; Danelli, Giorgio; Fierro, Giuseppe; De Cosmo, Germano; Servillo, Giovanni; Nuzzi, Massimiliano; Mentegazzi, Federico; Fanelli, Andrea; Martani, Carla; Spreafico, Emanuela; Pugliese, Francesco; Aceto, Paola; MONACO, FABRIZIO
- Source
- Subject
- Male
Monitoring
Hemodynamics
Pain
Cerebral oxygen saturation
Patient-Controlled
Anesthesia, General
Pacu
Oxygen Consumption
Postoperative Complications
Double-Blind Method
Monitoring, Intraoperative
Abdomen
Medicine
Humans
Anesthesia
Hemodynamic
Aged
Analgesia, Patient-Controlled
Anesthesia Recovery Period
Brain Chemistry
Female
Hypoxia, Brain
Oximetry
Pain, Postoperative
Prospective Studies
Anesthesiology and Pain Medicine
Postoperative
Prospective cohort study
General
Hypoxia
Intraoperative
biology
business.industry
Area under the curve
Brain
biology.organism_classification
Confidence interval
Prospective Studie
Postoperative Complication
Analgesia
business
Abdominal surgery
Human
- Language
- English
Elderly patients are more prone than younger patients to develop cerebral desaturation because of the reduced physiologic reserve that accompanies aging. To evaluate whether monitoring cerebral oxygen saturation (rSO(2)) minimizes intraoperative cerebral desaturation, we prospectively monitored rSO(2) in 122 elderly patients undergoing major abdominal surgery with general anesthesia. Patients were randomly allocated to an intervention group (the monitor was visible and rSO(2) was maintained at > or =75% of preinduction values; n = 56) or a control group (the monitor was blinded and anesthesia was managed routinely; n = 66). Cerebral desaturation (rSO(2) reduction