Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course
- Resource Type
- Authors
- Shinpei Nagata; Kazuhiro Kozumi; Shigeru Yamayoshi; Taiki Sato; Yoshitaka Ogata; Sung-Ho Kim; Takahiro Okusu; Suguru Yamamoto
- Source
- Internal medicine (Tokyo, Japan). 55(5)
- Subject
- 0301 basic medicine
Male
medicine.medical_specialty
Pediatrics
Thymoma
Autopsy
Asymptomatic
Hypogammaglobulinemia
03 medical and health sciences
0302 clinical medicine
Fatal Outcome
Agammaglobulinemia
hemic and lymphatic diseases
Internal Medicine
medicine
Sore throat
Humans
Aged
business.industry
Septic shock
Pharynx
Clinical course
Immunologic Deficiency Syndromes
Pharyngitis
General Medicine
Syndrome
Thymus Neoplasms
medicine.disease
Surgery
030104 developmental biology
medicine.anatomical_structure
030220 oncology & carcinogenesis
medicine.symptom
business
Agranulocytosis
- Language
- ISSN
- 1349-7235
Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial.