Overview of chronic myeloid leukemia patients in Pakistan in the pre-imatanib era
- Resource Type
- Authors
- Saad Z, Usmani; Shakeeb A, Yunus; Yasser, Jamal
- Source
- Asian Pacific journal of cancer prevention : APJCP. 10(6)
- Subject
- Adult
Male
Adolescent
Age Factors
Middle Aged
Piperazines
Pyrimidines
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Benzamides
Disease Progression
Imatinib Mesylate
Humans
Female
Pakistan
Protein Kinase Inhibitors
Aged
Retrospective Studies
- Language
- ISSN
- 2476-762X
To study the patient characteristics of patients diagnosed with chronic myelogenous leukemia (CML) at a tertiary care cancer hospital in Pakistan.A retrospective analysis was conducted on CML patients treated between 1996 and 2004 at Shaukat Khanum Memorial Cancer Hospital and Research Center.A total of 461 CML patient charts were reviewed. The mean and median ages at presentation were much younger than in the prior reports in the western literature with a quicker progression of disease.The advent of tyrosine kinase inhibitors will likely have more impact on the lifespan of CML patients in Pakistan when compared with patients in the western hemisphere due to younger age at diagnosis.