Degradable gold core–mesoporous organosilica shell nanoparticles for two-photon imaging and gemcitabine monophosphate delivery
- Resource Type
- Authors
- Saher Rahmani; Arnaud Chaix; Dina Aggad; Phuong Hoang; Niveen M. Khashab; Marcel Garcia; Magali Gary-Bobo; Basem Moosa; Clarence Charnay; Jean-Olivier Durand; Abdulaziz Almalik
- Source
- Mol. Syst. Des. Eng.. 2:380-383
- Subject
- Materials science
Process Chemistry and Technology
Biomedical Engineering
Energy Engineering and Power Technology
Nanoparticle
Nanotechnology
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Industrial and Manufacturing Engineering
Gemcitabine
0104 chemical sciences
Mesoporous organosilica
Two-photon excitation microscopy
Chemistry (miscellaneous)
Materials Chemistry
medicine
Chemical Engineering (miscellaneous)
Nanomedicine
0210 nano-technology
Luminescence
Gold core
medicine.drug
- Language
- ISSN
- 2058-9689
The synthesis of degradable gold core–mesoporous organosilica shell nanoparticles is described. The nanoparticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.