SO07 LAPAROSCOPIC VERSUS OPEN TOTAL MESORECTAL EXCISION: A CASE-CONTROL STUDY
- Resource Type
- Authors
- Jean-Pierre E. N. Pierie; C. Hoff; S. O. Breukink; A. J. K. Grond; T. Wiggers; W. J. H. J. Meijerink
- Source
- ANZ Journal of Surgery. 77:A87-A87
- Subject
- Laparoscopic surgery
medicine.medical_specialty
Preoperative radiotherapy
Colorectal cancer
business.industry
medicine.medical_treatment
Case-control study
General Medicine
medicine.disease
Total mesorectal excision
Circumferential margin
Surgery
Radiation therapy
Anastomotic leakage
medicine
business
- Language
- ISSN
- 1445-2197
1445-1433
Purpose Because definitive long-term results are not yet available, the oncological safety of laparoscopic surgery for treatment of rectal cancer remains unproven. The aim of this prospective non-randomized study was to assess the feasibility and short-term outcome of laparoscopic total mesorectal excision (LTME) after 25–30 Gy preoperative radiotherapy and to compare the results with a matched-control group of open TME (OTME). Methodology A series of 41 patients with primary rectal cancer underwent LTME for rectal cancer and were matched with a historical control group of 41 patients who underwent OTME. Both groups received preoperative short-term radiotherapy. Results There was no mortality in the LTME group and 2% mortality in the OTME group. The overall postoperative morbidity was 37% in the LTME group and 51% in the OTME group, including an anastomotic leakage of 9 and 14% in the LTME and OTME groups respectively. A positive circumferential margin was found in 7% of patients in the LTME group and in 12% of the patients in the OTME group. Conclusion This study shows that LTME is technically feasible and can be performed safely. We show at least a similar surgical completeness using a laparoscopic technique.