Russell Body Lesions of the Colon: Case Report and Literature Review
- Resource Type
- Authors
- Rizwan Kassam; Anita Gibbons; Anthony George; Phil Roberts; Syed Shaukat; W. Keith Tan; Rachel Charlotte Smith
- Source
- The Korean Journal of Gastroenterology, Vol 77, Iss 6, Pp 309-312 (2021)
- Subject
- Adenoma
Pathology
medicine.medical_specialty
Colorectal cancer
Plasma Cells
Russell bodies
monoclonal
State Medicine
03 medical and health sciences
0302 clinical medicine
Colon, Sigmoid
Tubulovillous adenoma
medicine
Humans
polyps
Multiple myeloma
Gastrointestinal tract
colon
business.industry
Amyloidosis
Sigmoid colon
General Medicine
Plasma cell neoplasm
medicine.disease
digestive system diseases
sigmoid
multiple myeloma
medicine.anatomical_structure
030220 oncology & carcinogenesis
Colonic Neoplasms
Medicine
030211 gastroenterology & hepatology
business
- Language
- ISSN
- 2233-6869
1598-9992
Russell bodies (RB) are rare manifestations within the lower gastrointestinal tract. To date, there are only three other reported cases of RB lesions of the colon; two were polyps, and the third was a case of a multifocal RB lesion of the gastrointestinal tract. This paper reports a case of a tubulovillous adenoma with RB of the sigmoid colon in a patient diagnosed incidentally as part of the UK National Health Service Bowel Cancer Screening Programme. A thorough hematological investigation is required to exclude hematological malignancies because of its association with plasma cell neoplasm. These lesions should undergo clonality analysis to exclude the monoclonal proliferation of plasma cells. Ideally, a bone marrow aspirate and investigations for amyloidosis should be performed to exclude underlying hematological malignancies. (Korean J Gastroenterol 2021;77:309-312)