Supplementary Table 1: Description of TCGA derived mRNA expression cohorts used to examine LIF expression and associated transcript signaturesSupplementary Table 2: Transcription signatures used to identify biological processes and cell types correlated with LIF expression.Supplementary Table 3: GSEA results of REACTOME pathway gene sets for enriched gene sets in LIF treated macrophages. Supplementary Table 4: Leading edge genes selected from GSEA analysis of LIF treated macrophages with REACTOME pathway gene sets Supplementary Table 5: Summary of data collection statistics for crystal structures of MSC-1:LIF co-complex Supplementary Table 6: Summary of interactions between MSC-1 and LIF