The Spectrum of Cutaneous Reactive Angiomatoses in End Stage Renal Failure
- Resource Type
- Authors
- Gorav Neel Wali; Radhika Bali; Eleni Ieremia
- Source
- The American Journal of dermatopathology. 43(8)
- Subject
- Pathology
medicine.medical_specialty
Angiomatosis
Cutaneous ulceration
Context (language use)
Dermatology
urologic and male genital diseases
Skin Diseases
Pathology and Forensic Medicine
Necrosis
Fatal Outcome
Skin Ulcer
medicine
Humans
Clinical significance
Vascular proliferation
Skin
Calciphylaxis
business.industry
General Medicine
Middle Aged
medicine.disease
Angiomatoses
End stage renal failure
Blood Vessels
Kidney Failure, Chronic
Female
business
- Language
- ISSN
- 1533-0311
Cutaneous reactive angiomatoses encompass a spectrum of conditions driven by underlying occlusive vasculopathy. We present 2 cases of reactive angioproliferation in the context of end-stage renal failure (ESRF) manifesting as painful cutaneous ulceration. The first case demonstrates histologic features of diffuse dermal angiomatosis. The second case illustrates a nonspecific pattern of vascular proliferation which does not conform to any of the classically described subtypes, therefore reinforcing the concept of a spectrum of histopathologic changes in reactive angioproliferations. Diffuse dermal angiomatosis has been described in ESRF alone and in association with calciphylaxis, a life-threatening condition. Recognizing the patterns of reactive angioproliferation in the context of ESRF therefore has clinical relevance. Earlier identification may facilitate mitigation of risk factors and improve prognosis.