Supplementary Figure S1: NMR Spectra of HA-Paclitaxel. 1H-NMR spectrum of HA-paclitaxel. Specific groups of HA-paclitaxel are shown with arrows; Supplementary Figure S2: Representative bioluminescent images of animals 24 hrs after intracardiac injection of the 231Br cells; Supplementary Figure S3: Representative image demonstrating that bioluminescence correlates well with histological location and burden of metastatic lesions in brain.