Electricity-induced micro-flow C–H/N–H alkyne annulation: a greener approach to access heteroaromatic compounds
- Resource Type
- Authors
- Bhushan Mahajan; Ajay Singh; Bhanwar Kumar Malviya; Pabbaraja Srihari; Genji Sukumar; Sanjeev Kumar
- Source
- Reaction Chemistry & Engineering. 6:1801-1805
- Subject
- Fluid Flow and Transfer Processes
chemistry.chemical_classification
Annulation
chemistry
Chemistry (miscellaneous)
business.industry
Process Chemistry and Technology
Chemical Engineering (miscellaneous)
Alkyne
Electricity
business
Combinatorial chemistry
Catalysis
- Language
- ISSN
- 2058-9883
Fast access to structurally diverse heteroaromatic compounds is demonstrated in an integrated continuous-flow manner without employing any expensive oxidant. The process involves an electro-flow heating reactor that uses electricity as the green oxidant to promote the reaction, leading to a fast (2 min) annulation reaction for the synthesis of heteroaromatic compounds.