Opioid-induced myoclonus and hyperalgesia following a short course of low-dose oral morphine
- Resource Type
- Authors
- Akriti Naraen; Owen Bleddyn Woodward; Sangeeta Naraen
- Source
- British journal of pain. 11(1)
- Subject
- medicine.medical_specialty
business.industry
Low dose
Myoclonic Jerk
Original Articles
Surgery
nervous system diseases
03 medical and health sciences
0302 clinical medicine
Anesthesiology and Pain Medicine
Opioid
030202 anesthesiology
Intravenous morphine
Anesthesia
Hyperalgesia
medicine
Oral morphine
medicine.symptom
Adverse effect
business
Myoclonus
030217 neurology & neurosurgery
medicine.drug
- Language
- ISSN
- 2049-4637
A 76-year-old man was admitted to hospital with a right-sided fractured neck of femur requiring repair via a cemented hemiarthroplasty. Intraoperatively he received 10 mg of intravenous morphine. Post-operatively he received a short course of low-dose oral opioids and subsequently developed myoclonic jerks and hyperalgesia. The opioids were discontinued and both adverse effects resolved. This case report discusses the concurrent development of myoclonus and hyperalgesia following a low dose of opioids and explores possible management options.