Sarcomatoid Carcinoma of the Urinary Bladder: A Clinicopathological Study of 4 Cases and a Review of the Literature
- Resource Type
- Authors
- Nerantzoula Petrakopoulou; Helen Moustou; Konstantinos Stamatiou; Ioannis Michailidis; Nikolaos Galariotis; Adamantia Zizi-Sermpetzoglou
- Source
- Korean Journal of Urology
- Subject
- Pathology
medicine.medical_specialty
Mesenchymal Differentiation
Urinary bladder
business.industry
Urinary bladder neoplasms
Case Report
medicine.disease
Resection
Transitional cell carcinoma
medicine.anatomical_structure
Bladder Tissue
medicine
Adjuvant therapy
Immunohistochemistry
business
Sarcomatoid carcinoma
- Language
- ISSN
- 2005-6737
Sarcomatoid carcinoma (SC) of urinary bladder is a rare tumor exhibiting aggressive behavior. Here we are reviewing the pathologic and clinical characteristics of 4 consecutive cases of this rare tumor. Three out of 4 patients were males and one female. The median age was 72.8 years (range, 60-79 years). Patients underwent transurethral resection of bladder tumor and the diagnosis of bladder SC was established on the pathologic examination of the resected bladder tissue. Despite treatment all patients died within 22 months of the diagnosis of SC. SC of the bladder are true biphasic malignant neoplasm exhibiting morphologic and immunohistochemical evidence of epithelial and mesenchymal differentiation with the presence or absence of heterologous elements. The aggressive of the tumor precludes radical therapy whenever possible, since adjuvant therapy seems to have little effect.