Performance of the Ultra-Compact Fully Integrated Brain PET System BPET
- Resource Type
- Authors
- Bruno Weber; Werner Lustermann; N. Kuegler; B. Sattler; M. L. Ahnen; G. Dissertori; O. Sabri; R. Becker; J. Soerensen; A. Buck; Jannis Fischer; E. Mikhaylova
- Source
- 2020 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC).
- Subject
- Physics
Photomultiplier
010308 nuclear & particles physics
business.industry
Image quality
01 natural sciences
Lyso
Imaging phantom
030218 nuclear medicine & medical imaging
03 medical and health sciences
Full width at half maximum
0302 clinical medicine
Silicon photomultiplier
Optics
Application-specific integrated circuit
0103 physical sciences
business
Image resolution
- Language
We present the prototype of a dedicated brain Positron Emission Tomography system BPET and the results of a first NEMA (NU2-2018 & NU4-2008) performance evaluation. BPET is a modular system, based on the PETA6SE application specific integrated circuit and LYSO crystals coupled in light sharing mode to silicon photomultipliers. All electronics are integrated into the detector head, which makes the system ultra-compact. The NU2-2018 spatial resolution in the axial center in [radial/tangential/axial] direction at r=10 mm is [4.0 / 3.9 / 3.5] mm full width at half maximum. The NU2-2018 system sensitivity is 2.9 cps/kBq for the smallest energy window at the radial center. It is 8.4 cps/kBq for the largest energy window considered at r=10 cm. We further show results of a noise equivalent count rate evaluation and BPET reconstructed images from a brain image quality phantom and a 3D Hoffman brain phantom. The performance characteristics of the BPET prototype are comparable to current clinical systems. BPET is the basis for the development of a clinical low-cost ultra-compact, fully integrated brain Positron Emission Tomography system.