Targeting Constitutively Active STAT3 in Chronic Lymphocytic Leukemia: A Clinical Trial of the STAT3 Inhibitor Pyrimethamine with Pharmacodynamic Analyses
- Resource Type
- Source
- Am J Hematol
- Subject
Adult Male STAT3 Transcription Factor Chronic lymphocytic leukemia Constitutively active Antineoplastic Agents Pharmacology Stat3 inhibitor Article Text mining Cell Line, Tumor Medicine Humans STAT3 Aged Aged, 80 and over B-Lymphocytes biology Dose-Response Relationship, Drug business.industry Gene Expression Regulation, Leukemic Gene Expression Profiling Drug Repositioning Hematology Middle Aged medicine.disease Leukemia, Lymphocytic, Chronic, B-Cell Progression-Free Survival Neoplasm Proteins Clinical trial Pyrimethamine Pharmacodynamics biology.protein Female Drug Screening Assays, Antitumor business medicine.drug - Language
- English