An analysis and interpretation of experimental and theoretical data on the spectral-luminescent, photophysical, and photochemical properties of dipyrromethenates are presented depending on the structure of the ligand, the complexing agent type, and the solvent and its phase state (temperature). The special features of photonics related to the violation of the physicochemical properties in the series of substituted dipyrromethenates in heteroatoms and heavy atoms (their nature, location, and the number of such substituents) are discussed.