Should patients with an incidental finding of focal myocardial 18FDG uptake be screened by myocardial perfusion scintigraphy?
- Resource Type
- Authors
- D. De Verbizier; Aurélie Bourdon; Meriem Benkiran; Nicolas Molinari; Vincent Boudousq; Denis Mariano-Goulart; T. Fidani; Fabien Vauchot
- Source
- Médecine Nucléaire
Médecine Nucléaire, Elsevier/Masson, 2020, ⟨10.1016/j.mednuc.2020.02.002⟩
- Subject
- medicine.medical_specialty
Myocardial ischemia
Radiological and Ultrasound Technology
business.industry
Biophysics
Ischemia
medicine.disease
3. Good health
030218 nuclear medicine & medical imaging
Coronary artery disease
03 medical and health sciences
Basal (phylogenetics)
0302 clinical medicine
Internal medicine
Right coronary artery
medicine.artery
Myocardial perfusion scintigraphy
Cardiology
[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Medicine
Radiology, Nuclear Medicine and imaging
In patient
Abnormality
business
- Language
- English
- ISSN
- 0928-1258
International audience; Purpose. – Focal F-18-fluoro-deoxy-glucose uptake in the myocardium can be a sign of resting myocardial ischemia. The purpose of our study was to assess the relevance of performing myocardial perfusion scintigraphy to screen for myocardial ischemia in patients with an incidental finding of focal myocardial F-18-fluoro-deoxy-glucose uptake on a routine F-18-fluoro-deoxy-glucose positron- emission-tomography-computed-tomography.Methods. – In our retrospective multicentric study, patients were included if they had had an incidental finding of myocardial focal F-18-fluoro-deoxy-glucose uptake on a routine F-18-fluoro-deoxy-glucose positron-emission-tomography-computed-tomography and had also undergone myocardial perfusion scintigraphy within 3 months before or after the F-18-fluoro-deoxy-glucose positron-emission- tomography-computed-tomography. Patients with a pattern of ischemia or scar on the myocardial perfusion scintigraphy in the same territory as the focal F-18-fluoro-deoxy-glucose uptake were considered positive.Results. – Seven of the 34 included patients were positive, with an abnormality on the MPS data in the same territory as the focal myocardial F-18-fluoro-deoxy-glucose uptake. 2 of the 6 patients with focal F- 18-fluoro-deoxy-glucose uptake in the left anterior descending vascular supply territory and 2 of the 4 patients with focal F-18-fluoro-deoxy-glucose uptake in the standard right coronary artery territory had an abnormal myocardial perfusion scintigraphy. All 12 patients with focal F-18-fluoro-deoxy- glucose uptake restricted to the basal anterolateral and basal inferolateral segments were negative. Conclusion. – PatientswithanincidentalfindingoffocalF-18-fluoro-deoxy-glucoseuptakeonaroutine F-18-fluoro-deoxy-glucose positron-emission-tomography-computed-tomography may be considered as being at risk for coronary artery disease, when this uptake is multisegmentary in the same typical coronary territory and not restricted to the basal anterolateral and basal inferolateral segments.