Multicomponent Analysis of Replacement Liquids of Electronic Cigarettes Using Chromatographic Techniques
- Resource Type
- Authors
- Dimitrios Kouretas; Matthaios Kavvalakis; Manolis Tzatzarakis; Jyrki Liesivuori; Athanasios Alegakis; Dionysios Vynias; Polychronis Stivaktakis; Aristidis Tsatsakis
- Source
- Journal of Analytical Toxicology. 39:262-269
- Subject
- Glycerol
Quality Control
Nicotine
Analyte
Nitrosamines
Acyclic Monoterpenes
Health, Toxicology and Mutagenesis
Analytical chemistry
Electronic Nicotine Delivery Systems
ta3111
Toxicology
Mass spectrometry
Gas Chromatography-Mass Spectrometry
Analytical Chemistry
chemistry.chemical_compound
Limit of Detection
Environmental Chemistry
Polycyclic Aromatic Hydrocarbons
Flavor
Chemical Health and Safety
Chromatography
Reproducibility of Results
Propylene Glycol
ta3124
chemistry
Monoterpenes
Ethylene Glycols
Chromatography, Liquid
- Language
- ISSN
- 1945-2403
0146-4760
The electronic cigarette (e-cig) is an invention of the past few years and its popularity is rapidly growing all over the world. A rapid multicomponent analytical protocol for the analysis of the replacement liquids (e-liquids) of e-cig was developed using gas (GC) and liquid chromatography (LC) – mass spectrometry (MS). GC – MS-based methods were developed for the determination of the main humectants and polycyclic aromatic hydrocarbons (PAHs). For the determination and quantification of nicotine (NIC) and nitrosamines, appropriate LC– MS-based methods were developed. The approbated methods were applied for the analysis of 263 e-liquid samples obtained from the Greek market. The instruments response was linear; the limits of quantification ranged from 0.003 mg/mL for three PAHs to 1.187 mg/mL for glycerol. The precision was