Acute Gastrointestinal Injury
- Resource Type
- Authors
- Pietro Fransvea; Margherita Loponte; Simone Rossi Del Monte; Francesco Cortese; Stefano Rossi; Biagio Picardi
- Source
- Infections in Surgery ISBN: 9783030621155
- Subject
- medicine.medical_specialty
Gastrointestinal tract
Abdominal compartment syndrome
Critically ill
business.industry
Abdominal Infection
Gastrointestinal Injury
Gastrointestinal failure
medicine.disease
Pathophysiology
medicine
Multiple organ dysfunction syndrome
Intensive care medicine
business
- Language
“It’s all in the gut” says Manu Malbrain. In light of this aphorism, the acknowledgment and the understanding of mechanisms of gastrointestinal pathophysiology has led to the codification of the concept of gastrointestinal failure and the definition of Acute Gastrointestinal Injury (AGI). Undoubtedly, the intestine plays an important role in the development of sepsis syndrome and MOF. Modification of the gut barrier seems to occur clinically and to be responsible for the increased prevalence of infectious complications in critically ill patients. The term “Acute Gastrointestinal Injury” (AGI) has been proposed to address GI dysfunction as part of the multiple organ dysfunction syndrome in critically ill patients, whether or not they have primary abdominal pathology.