A Model of Colonic Crypts using SBML Spatial
- Resource Type
- Authors
- Daniele Ramazzotti; Marco Antoniotti; Carlo Maj
- Source
- Electronic Proceedings in Theoretical Computer Science, Vol 130, Iss Proc. Wivace 2013, Pp 74-78 (2013)
WIVACE
- Subject
- FOS: Computer and information sciences
Computational model
Human intestine
Computer science
Systems Biology
lcsh:Mathematics
Molecular Networks (q-bio.MN)
Crypt
Exchange Format
Computational biology
lcsh:QA1-939
lcsh:QA75.5-76.95
Computational Engineering, Finance, and Science (cs.CE)
FOS: Biological sciences
Quantitative Biology - Molecular Networks
lcsh:Electronic computers. Computer science
SBML
Computer Science - Computational Engineering, Finance, and Science
Simulation
- Language
The Spatial Processes package enables an explicit definition of a spatial environment on top of the normal dynamic modeling SBML capabilities. The possibility of an explicit representation of spatial dynamics increases the representation power of SBML. In this work we used those new SBML features to define an extensive model of colonic crypts composed of the main cellular types (from stem cells to fully differentiated cells), alongside their spatial dynamics.
Comment: In Proceedings Wivace 2013, arXiv:1309.7122