In vitro synthesis of IgG by cells from the cerebrospinal fluid in a patient with multiple sclerosis
- Resource Type
- Authors
- M, Sandberg-Wollheim; O, Zettervall; R, Müller
- Source
- Clinical and experimental immunology. 4(4)
- Subject
- Adult
Electrophoresis
Multiple Sclerosis
Leucine
Culture Techniques
Immunoglobulin G
Humans
Female
Articles
Tritium
Cerebrospinal Fluid
- Language
- ISSN
- 0009-9104
Mononuclear cells of the cerebrospinal fluid from a patient with multiple sclerosis were maintained in vitro for 5 days. Synthesis of IgG occurred and was significantly higher during a relapse of the disease than during remissions. The electrophoretic IgG species that were found in the cerebrospinal fluid of the patient were also synthesized in vitro.