Prevalence of Endocrine Disorders in Childhood Brain Tumor Survivors in South Korea
- Resource Type
- Authors
- Jun Eun Park; Jaesung Heo; Logyoung Kim; Hae Sang Lee; Jin Son Hwang; O Kyu Noh
- Source
- In Vivo. 33:2287-2291
- Subject
- Male
Cancer Research
Pediatrics
medicine.medical_specialty
Longitudinal study
Adolescent
Psychological intervention
Hypopituitarism
Endocrine System Diseases
Logistic regression
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
0302 clinical medicine
Cancer Survivors
Republic of Korea
Prevalence
medicine
Humans
Endocrine system
Child
Pharmacology
Brain Neoplasms
business.industry
Infant, Newborn
Disease Management
Infant
Odds ratio
medicine.disease
Pediatric cancer
Child, Preschool
Population Surveillance
030220 oncology & carcinogenesis
Cohort
Female
business
Research Article
- Language
- ISSN
- 1791-7549
0258-851X
Background/Aim: This longitudinal study aimed to analyze the prevalence of endocrine disorders in childhood brain tumor survivors in South Korea using claims data. Patients and Methods: We identified in 1,058 patients from a nationwide cohort of patients diagnosed with brain tumors between January 1st 2009 to March 29th 2016. Multivariable logistic regression was used to evaluate associations between clinical factors and endocrine disorders. Results: After a median follow-up of 60.0 months, 393 (37.1%) patients had at least 1 endocrine disorder. The commonest endocrine disorders were hypopituitarism (17.4%) and hypothyroidism (6.1%). Female gender (odds ratio(OR)=1.45, p=0.005) and age