Additional file 1 of Evaluation of the effects of acetylcholinesterase inhibitors in the zebrafish touch-evoked response: quantitative vs. qualitative assessment
- Resource Type
- Authors
- Guzman, Laura; Besa, Gisela; Linares, Daniela; González, Lara; Pont, Caterina; Bartolini, Manuela; Ann-Cathrin Haigis; Legradi, Jessica; Muñoz-Torrero, Diego; Gómez-Catalán, Jesús; Barenys, Marta
- Source
- Subject
- animal structures
embryonic structures
- Language
Additional file 1: Figure S1. Chemical structure of huprine Y and general structure of the huprine derivatives 1-10. Figure S2. Evaluation of the TER in controls with (1%) and without DMSO. Figure S3. Quantitative evaluation of the touch-evoked response assay. Figure S4. Comparison of control qualitative values of the touch-evoked response assay performed at 72 or 96 hpf and evaluated using the 0–4 or 0–6 scoring system (n72hpf=214; n96hpf=90). Table S1. Calculated molecular properties of the tested compoundsa. Table S2. Detailed description of the procedure followed to quantitatively evaluate the TER in zebrafish embryos using ImageJ. Table S3. Structural dysmorphogenesis (in % ±SD) of zebrafish embryos exposed to the tested compounds in the embryotoxicity assay. Table S4. Percentage of mortality (±SD) of zebrafish embryos exposed to the tested compounds.