Objective: Characterize the types and doses of commonly administered perioperative drugs in inguinal hernia (IH) repair for premature infants. Study Design: Single-center, retrospective cohort study Results: In total, 112 premature infants underwent IH repair between 2010–2015. Twenty-one drugs were used during IH repair, with each infant receiving a median 7 drugs. Acetaminophen (88%), bupivacaine (84%), cisatracurium (74%), sevoflurane (72%), and propofol (71%) were the most commonly used agents. Thirty-two infants underwent additional procedures with IH repair. Additional procedures were not associated with a higher number of perioperative drugs, however infants with additional procedures were exposed to higher cumulative doses of cisatracurium (p