Additional file 1 of Macrophage-mediated tissue response evoked by subchronic inhalation of lead oxide nanoparticles is associated with the alteration of phospholipases C and cholesterol transporters
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- Smutná, Tereza; Dumková, Jana; Kristeková, Daniela; Laštovičková, Markéta; Jedličková, Adriena; Vrlíková, Lucie; Dočekal, Bohumil; Alexa, Lukáš; Kotasová, Hana; Pelková, Vendula; Večeřa, Zbyněk; Křůmal, Kamil; Petráš, Jiří; Coufalík, Pavel; Všianský, Dalibor; Záchej, Samuel; Pinkas, Dominik; Vondráček, Jan; Hampl, Aleš; Mikuška, Pavel; Buchtová, Marcela
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Additional file 1. Calculation of deposited dose of PbO nanoparticles. Figure S1. Analysis of weight of target organs after exposure to PbO NPs. Table S1: Pathological changes in kidney 11-week PbO NP inhalation. Table S2. Pathological changes in lung after 11-week PbO NP inhalation. Table S3: Analysis of macrophage numbers in lungs. Table S4: Pathological changes in liver after 11-week PbO NP inhalation. Figure S2: Statistical evaluation of histopathological changes in liver after 11 weeks of PbO NP inhalation. Table S5: Analysis of macrophage numbers in liver. Figure S3: Spleen after 11-week PbO NP inhalation. Table S6: Analysis of megakaryoblasts and megakaryocytes in spleen. Figure S4: Statistical evaluation of megakaryoblasts and megakaryocytes in spleen. Table S7: List of antibodies used for immunohistochemical analysis.