Hit-to-lead studies on benzimidazole inhibitors of ITK: discovery of a novel class of kinase inhibitors
- Resource Type
- Source
- Bioorganicmedicinal chemistry letters. 17(13)
- Subject
Benzimidazole Stereochemistry High-throughput screening Chemistry, Pharmaceutical Clinical Biochemistry Drug Evaluation, Preclinical Pharmaceutical Science Plasma protein binding Biochemistry chemistry.chemical_compound Inhibitory Concentration 50 Structure-Activity Relationship Adenosine Triphosphate Drug Discovery Structure–activity relationship Humans Binding site Enzyme Inhibitors Molecular Biology Protein Kinase Inhibitors chemistry.chemical_classification Binding Sites biology Organic Chemistry Hydrogen Bonding Hit to lead Protein-Tyrosine Kinases Enzyme chemistry Models, Chemical Enzyme inhibitor biology.protein Molecular Medicine Benzimidazoles Protein Binding - Language
- ISSN
- 0960-894X