Burden and etiology of moderate and severe diarrhea in children less than 5 years of age living in north and south of China: Prospective, population-based surveillance
- Resource Type
- Authors
- Jing-Chen Ma; Leslie Barclay; Baoming Jiang; Can-Jing Zhang; Yu-Liang Zhao; Song-Mei Wang; Xuan-Yi Wang; Zhao-Jun Mo; Theresa K. Bessey; Gan Zhao; Rong-Cheng Li; Jin-Xia Wang; Hong-Lu Zhou; Chao Qiu
- Source
- Gut Pathogens, Vol 13, Iss 1, Pp 1-11 (2021)
Gut Pathogens
- Subject
- Diarrhea
0301 basic medicine
China
medicine.medical_specialty
Etiology
030106 microbiology
Population
Burden
RC799-869
medicine.disease_cause
Microbiology
Astrovirus
03 medical and health sciences
0302 clinical medicine
Medical microbiology
Virology
Rotavirus
Internal medicine
Medicine
030212 general & internal medicine
education
Children
education.field_of_study
biology
business.industry
Research
Campylobacter
Gastroenterology
Sapovirus
Diseases of the digestive system. Gastroenterology
biology.organism_classification
Infectious Diseases
Enteroaggregative Escherichia coli
Parasitology
medicine.symptom
business
- Language
- ISSN
- 1757-4749
Background Diarrhea remains the leading cause of childhood illness in China. Better understanding of burden and etiology of diarrheal diseases is important for development of effective prevention measures. Methods Population-based diarrhea surveillance was conducted in Sanjiang (southern China) year-round and Zhengding (northern China) in autumn/winter. Stool specimens were collected from children
Key Points Currently bacterial and viral agents in the gastrointestinal tract are under-detected and poorly defined in developing countries. A new sensitive TAC assay provided comprehensive identification of microorganisms, including neglected pathogens, in Chinese children with moderate and severe diarrhea. Supplementary Information The online version contains supplementary material available at 10.1186/s13099-021-00428-2.