Improving on the Ability of Endogenous Hepatitis B Core Antigen to Prime Cytotoxic T Lymphocytes
- Resource Type
- Authors
- Jessica Nystroöm; Gustaf Ahlén; Michael Fons; Catharina Hultgren; Antony Chen; David R. Milich; Darrell L. Peterson; Sarene Koh; Anette Brass; Lars Frelin; Matti Sällberg
- Source
- The Journal of Infectious Diseases. 201:1867-1879
- Subject
- CD4-Positive T-Lymphocytes
Hepatitis B virus
Helper T lymphocyte
Dose-Response Relationship, Immunologic
Priming (immunology)
chemical and pharmacologic phenomena
Hepacivirus
Biology
Lymphocyte Activation
Transfection
medicine.disease_cause
Mice
Antigen
medicine
Animals
Immunology and Allergy
Cytotoxic T cell
Hepatitis B Antibodies
Mice, Inbred BALB C
Viral Core Proteins
virus diseases
T-Lymphocytes, Helper-Inducer
T helper cell
Hepatitis B Core Antigens
Virology
digestive system diseases
Mice, Inbred C57BL
CTL
HBcAg
Electroporation
Infectious Diseases
medicine.anatomical_structure
Immunoglobulin G
DNA, Viral
Immunology
T-Lymphocytes, Cytotoxic
- Language
- ISSN
- 1537-6613
0022-1899
Hepatitis B virus core antigen (HBcAg) is thought to be a major target for specific cytotoxic T cells (CTLs) in hepatitis B virus infections. A single dose of hepatitis C virus nonstructural 3/4A DNA (