An efficient planning technique for low dose whole lung radiation therapy for covid-19 pandemic patients
- Resource Type
- Authors
- Michael P. Hagan; Jatinder R. Palta; Lulin Yuan; Siyong Kim
- Source
- Physics and Imaging in Radiation Oncology, Vol 16, Iss, Pp 85-88 (2020)
Physics and Imaging in Radiation Oncology
- Subject
- lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Dose calculation
medicine.medical_treatment
lcsh:R895-920
lcsh:RC254-282
Article
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Tissue heterogeneity
medicine
Radiology, Nuclear Medicine and imaging
LDIR
Monitor unit
Radiation
Lung
medicine.diagnostic_test
business.industry
Low dose
Efficient planning technique
respiratory system
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Lung consolidation
Radiation therapy
medicine.anatomical_structure
Radiology Nuclear Medicine and imaging
030220 oncology & carcinogenesis
COVID-19 pandemic patients
Radiology
Low dose whole lung radiation therapy
Chest radiograph
business
- Language
- English
- ISSN
- 2405-6316
Highlights • An efficient planning technique for low dose whole lung treatment is developed to reduce the hyper-inflammatory reaction and mortality for severe COVID-19 patients. • An empirical formula to calculate MU from patient body thickness and lung consolidation was fitted from actual CT images of clinical patients with different levels of lung density overrides. • 3D dose calculation in real patient anatomy with heterogeneity correction shows that the dose in the lungs has acceptable uniformity with this simple and straightforward technique.
This study aimed to establish an efficient planning technique for low dose whole lung treatment that can be implemented rapidly and safely. The treatment technique developed here relied only on chest radiograph and a simple empirical monitor unit calculation formula. The 3D dose calculation in a real patient anatomy, including both nonCOVID and COVID-19 patients, which took into account tissue heterogeneity showed that the dose delivered to lungs had reasonable uniformity even with this simple and quick setup.