Activity of disinfectants against multispecies biofilms formed byStaphylococcus aureus,Candida albicansandPseudomonas aeruginosa
- Resource Type
- Authors
- Heleen Van Acker; Sarah Tavernier; Didem Kart; Tom Coenye; Hans Nelis
- Source
- Biofouling. 30:377-383
- Subject
- Staphylococcus aureus
Biofouling
Disinfectant
Aquatic Science
medicine.disease_cause
Applied Microbiology and Biotechnology
Microbiology
Human health
Candida albicans
medicine
Water Science and Technology
Microbial Biofilms
biology
Pseudomonas aeruginosa
Multispecies biofilms
Biofilm
Gene Expression Regulation, Bacterial
biochemical phenomena, metabolism, and nutrition
biology.organism_classification
Oxidative Stress
Genes, Bacterial
Biofilms
Reactive Oxygen Species
Disinfectants
- Language
- ISSN
- 1029-2454
0892-7014
Microbial biofilms are a serious threat to human health. Recent studies have indicated that many clinically relevant biofilms are polymicrobial. In the present study, multispecies biofilms were grown in a reproducible manner in a 96-well microtiter plate. The efficacy of nine commercially available disinfectants against Staphylococcus aureus, Candida albicans, and Pseudomonas aeruginosa in multispecies biofilms was determined and compared. The results showed that the direction and the magnitude of the effect in a multispecies biofilm depend on the strain and the disinfectant used and challenge the common belief that organisms in multispecies biofilms are always less susceptible than in monospecies biofilms.