An integrative literature review of research into the psychosocial factors which shape the transition to parenthood in couples following non-donor in vitro fertilisation in comparison with spontaneously conceiving couples was undertaken following adapted PRISMA guidelines. Nineteen papers of non-donor IVF and SC mothers and fathers were included in the review. \ud \ud This is the first review to report on research comparing the transition to parenthood of couples following successful non-donor singleton AR and SC couples. The small number of studies were over reliant on survey methodologies. Differences between groups were reported on a range of psychosocial measures during the transition from pregnancy to parenthood: locus of control, parental adjustment and child behaviour, parental stress, parental investment in the child, self-esteem and self-efficacy, greater levels of protectiveness (separation anxiety) towards child, marital and family functioning, family alliance, marital satisfaction and communication as well anxiety, indirect aggression and less respect for child.\ud \ud We have conceptualised these differences as three substantive themes which reflect psychosocial factors shaping transition to parenthood in parents after non-donor AR: social support, relationships, and emotional well-being which are in turn intersected by gender differences. These findings have implications for health care professionals’ assessment of individual couples’ support needs.