The research spans several application areas, including biotechnology, medical imaging, and environmental monitoring. Precise and specialized processing techniques are often required for measurements of signal parameters with high efficiency, for example, in terms of resolution and count rate, such as time of occurrence of events. Digital solutions have thus received the most significant attention since they are the most effective at enabling flexible, application-oriented elaboration systems. The research is finalized to develop high-resolution time measurement systems in Field Programmable Gate Array (FPGA) devices. The goal is to optimize resolution, linearity, and processing speed at the state-of-the-art in modern, most dynamic branches of very high-efficiency time measurement. To maximize the number of events handled in real-time, the research is also concentrated on developing cutting-edge communication and data transfer methods for performing multiple measures in parallel.