Preoperative CT in patients with surgically resectable pancreatic adenocarcinoma: does the time interval between CT and surgery affect survival?
- Resource Type
- Authors
- Gerard M. Healy; Edmund Ronan Ryan; Dermot E. Malone; Hannah Fleming; C. E. Redmond; S. Murphy; A. Haughey; Kevin C. Conlon; Richard G. Kavanagh; Niall Swan
- Source
- Abdominal Radiology. 43:620-628
- Subject
- Male
medicine.medical_specialty
endocrine system diseases
Urology
medicine.medical_treatment
Population
Adenocarcinoma
Time-to-Treatment
03 medical and health sciences
Pancreatectomy
0302 clinical medicine
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
In patient
education
Aged
Retrospective Studies
education.field_of_study
Radiological and Ultrasound Technology
Proportional hazards model
business.industry
Gastroenterology
Middle Aged
Hepatology
Prognosis
medicine.disease
Neoadjuvant Therapy
humanities
Intention to Treat Analysis
Surgery
Pancreatic Neoplasms
Survival Rate
Radiation therapy
Periampullary Adenocarcinoma
030220 oncology & carcinogenesis
Cohort
Disease Progression
Female
030211 gastroenterology & hepatology
Radiology
Tomography, X-Ray Computed
business
- Language
- ISSN
- 2366-0058
2366-004X
The preoperative imaging-to-surgery time interval (ISI) influences the risk of unexpected progression (UP) found at surgery for pancreatic adenocarcinoma. We aimed to assess whether ISI influences disease recurrence and/or survival. A single-institution, ethics board-approved retrospective analysis of all patients who underwent attempted resection of pancreatic (PDAC) or periampullary adenocarcinoma (AmpAC) between 1st January 2010 and 31st December 2015 was performed. All patients underwent preoperative abdominal computed tomography (CT). Exclusion criteria were borderline resectable disease and neoadjuvant chemo/radiotherapy. Patients were followed up until 30th June 2016. The population was divided into ISI ≥/