Altering Iodine Metabolism in the Calf by Feeding Iodine-Binding Agents
- Resource Type
- Authors
- E.W. Swanson; W.F. Byrne; J.K. Miller; W.A. Lyke
- Source
- Journal of Dairy Science. 58:931-937
- Subject
- medicine.medical_specialty
Cottonseed Oil
Injections, Subcutaneous
Administration, Oral
chemistry.chemical_element
Urine
Iodine
Iodine Radioisotopes
Excretion
Feces
Animal science
Oral administration
Internal medicine
Blood plasma
Genetics
medicine
Animals
Cottonseed meal
Anion Exchange Resins
Dose-Response Relationship, Drug
Chemistry
Feces analysis
Endocrinology
Injections, Intravenous
Cattle
Animal Science and Zoology
Ion Exchange Resins
Digestive System
Food Science
- Language
- ISSN
- 0022-0302
Effects of feeding cottonseed meal and anion-exchange resin on iodine absorption and excretion by calves were investigated. Each additional amount of resin fed from .3 to 3.5 g/kg body weight further increased fecal excretion from single oral iodine-131 and intravenous iodine-125 doses. By feeding 3 to 10 g cottonseed meal/kg body weight, excretion of oral iodine-131 given daily was increased 7 to 94% in feces and reduced as much as 35% in urine, but plasma iodine-131 was not changed. Introducing 1 g resin/kg body weight daily into the diet increased fecal iodine-131 excretion three to five times that with cottonseed meal alone and reduced both plasma and urinary iodine-131. The same amount of resin fed daily had similar effects on excretion of iodine-131 injected subcutaneously each day. Although iodine depletion by a highly efficient iodine binder (resin) in the gastrointestinal tract is probable, iodine binding by a natural feed constituent (cottonseed meal) was relatively inefficient.