Introduction: Heart failure (HF) is the reason for the ever increasing number in hospitalization. Elderly age, comorbidities and currently ongoing COVID-19 pandemic result in fewer hospitalizations, more severe clinical presentation and more deaths in times of pandemic. Aim: To compare the relations between different clinical parameters of 133 patients hospitalized at the Clinic for Cardiovascular Diseases, Clinical Hospital Centre Rijeka, Croatia in the period between January 1, 2021 and April 1, 2021. and cross-reference it with the data from the 150 patients in the same quarterly period in 2019. To determine heart-focused anxiety and anxiety symptoms, depressive symptoms and intolerance of uncertainty using standardized psychological questionnaire in patients hospitalized for HF in 2021. Results: There were no statistically significant differences in age, gender, body mass index, NYHA class, heart rate and left ventricular ejection fraction between patients hospitalized during the 2021 pandemic compared to the 2019 pre- pandemic group. There was statistically significant higher blood pressure (p