The development of mining to acquire the best raw materials for producing stone tools represents a breakthrough in human technological and intellectual development. We present a new approach to studying the history of flint mining, using in situ -produced cosmogenic 10 Be concentrations. We show that the raw material used to manufacture flint artifacts ≈300,000 years old from Qesem Cave (Israel) was most likely surface-collected or obtained from shallow quarries, whereas artifacts of the same period from Tabun Cave (Israel) were made of flint originating from layers 2 or more meters deep, possibly mined or quarried by humans.