Healthy elderly in clinical trials: how to define preclinical Alzheimer’s Disease for clinical trial participation
- Resource Type
- Authors
- Prins, S.
- Source
- None
- Subject
- Clinical trials
Neuroinflammation
Neurodegeneration
Preclinical Alzheimer's Diseases
Biomarkers
Healthy elderly
- Language
- English
How to define the preclinical Alzheimer's Disease state in otherwise healthy elderly. How to best select otherwise healthy elderly for clinical trials participation with a disease modifiying compound. Difference between healthy elderly and subjects in the preclinical AD stage on biomarker level. Difference in cognitive performance in healthy subjects compared to neurodegenerative disease profiles.