Continuous Positive Airway Pressure Use for Obstructive Sleep Apnea in Acute, Traumatic Tetraplegia
- Resource Type
- Authors
- Graco, M; Schembri, R; Ross, J; Green, SE; Booker, L; Cistulli, PA; Ayas, NT; Berlowitz, DJ; COSAQ Investigators
- Source
- Subject
- Adult
Male
Sleep Apnea, Obstructive
Continuous Positive Airway Pressure
Rehabilitation
Middle Aged
1103 Clinical Sciences, 1106 Human Movement and Sports Sciences, 1117 Public Health and Health Services
Quadriplegia
Severity of Illness Index
Humans
Patient Compliance
Female
Spinal Cord Injuries
Aged
- Language
- English
OBJECTIVE: To describe continuous positive airway pressure (CPAP) use for treatment of obstructive sleep apnea (OSA) in acute tetraplegia, including adherence rates and associated factors. DESIGN: Secondary analysis of CPAP data from a multinational randomized controlled trial. SETTING: Inpatient rehabilitation units of 11 spinal cord injury centers. PARTICIPANTS: People with acute, traumatic tetraplegia and OSA (N=79). INTERVENTIONS: Autotitrating CPAP for OSA for 3 months. MAIN OUTCOME MEASURES: Adherence measured as mean daily hours of use. Adherent (yes/no) was defined as an average of at least 4 hours a night throughout the study. Regression analyses determined associations between baseline factors and adherence. CPAP device pressure and leak data were analyzed descriptively. RESULTS: A total of 79 participants from 10 spinal units (91% men; mean age ± SD, 46±16; 78±64d postinjury) completed the study in the treatment arm and 33% were adherent. Mean daily CPAP use ± SD was 2.9±2.3 hours. Better adherence was associated with more severe OSA (P=.04) and greater CPAP use in the first week (P