1. The four common theoretical principles found in principlism are: beneficence; non-maleficence; respect for autonomy; justice. 2. All interventions have more than one outcome. When making a decision to intervene, it is possible to know about all the outcomes without intending all of them, but that only avoids moral responsibility for the outcome if the decision (such as the dose, or the risk of an adverse effect relative to the likelihood of a good one) is proportionate to what was intended. 3. Justice is a universal principle that is equally applicable in countries that are resource rich and those that are not. 4. Some children will always die from cancer. Justice demands that maintaining the quality of a child’s life, once cure from cancer is highly unlikely should be given the same financial priority as attempts to treat it while cure seems possible.