Oral hairy leukoplakia arising in a patient with hairy cell leukaemia: the first reported case
- Resource Type
- Authors
- Konrad Staines; Alexandra Perks; Gemma Davis; Pemith Liyanage
- Source
- BMJ Case Reports. :bcr-2016
- Subject
- Male
Epstein-Barr Virus Infections
medicine.medical_specialty
Leukoplakia, Hairy
Dentistry
Asymptomatic
Article
Virus
03 medical and health sciences
0302 clinical medicine
Immune system
Pathognomonic
Tongue
Cytology
medicine
Humans
B cell
Leukemia, Hairy Cell
Oral hairy leukoplakia
business.industry
030206 dentistry
General Medicine
Middle Aged
Dermatology
medicine.anatomical_structure
Purines
030220 oncology & carcinogenesis
medicine.symptom
business
Lichen Planus, Oral
- Language
- ISSN
- 1757-790X
Oral hairy leukoplakia (OHL) is an oral mucosal lesion that is associated with Epstein-Barr virus infection. It commonly presents as an asymptomatic, non-removable white patch on the lateral borders of the tongue in individuals who are immunocompromised. Historically, OHL was thought to be pathognomonic of HIV infection; however, it is now an established phenomenon in a range of conditions affecting immune competence. Hairy cell leukaemia (HCL) is a rare chronic B cell lymphoproliferative disease named after the distinctive cytology of the atypical cells. We report the first case of OHL arising in an individual with HCL that resolved following remission of the haematological malignancy.