Demographic factors in extreme good and extreme poor prognosis patient groups (in samples for which data was available). Table S2. Genes deregulated in extreme poor prognosis PTC patients relative to extreme good prognosis patients. Table S3. Differential expression of prognostic genes in normal tissue, extreme good prognosis cancers and extreme poor prognosis cancers. Table S4. Genes consistently upregulated or downregulated [1] in extreme poor prognosis patients in leave-one-out cross validation. Table S5. Genes downregulated in poor-prognosis PTC & overlapping with published (referenced) gene-sets. Table S6. Distribution of clinicopathologic and demographic factors in intermediate risk patients classified as good or poor prognosis by PAM model (All samples). Table S7. Distribution of clinical characteristics of intermediate good and intermediate poor prognosis groups in leave-one-out cross validation. Table S8. Genes used within the PAM classifier, and presence [1] or absence (0) of each gene within classifier, when patients representing each of 6 poor prognostic factors are left out. (PDF 1097Â kb)