The relationship between maternal and umbilical cord adropin levels with the presence and severity of preeclampsia
- Resource Type
- Authors
- Burcu Dincgez Cakmak; Gülten Özgen; Yasin Altekin; Robab Ahmedian; Tayfur Çift; Betul Dundar; Abdullah Serdar Acikgoz
- Source
- Journal of Perinatal Medicine. 45:879-885
- Subject
- Fetus blood
0301 basic medicine
Adenosine
Unclassified drug
Enzyme linked immunosorbent assay
Expression
Maternal
Growth
Pediatrics
Umbilical cord
Umbilical cord blood
0302 clinical medicine
Nitric-oxide
Pre-Eclampsia
Pregnancy
Obstetrics & gynecology
Priority journal
030219 obstetrics & reproductive medicine
Plasma adropin
Correlation analysis
Obstetrics and Gynecology
Gestational age
Pregnancies
Blood Proteins
Fetal Blood
Chemistry
Blood
medicine.anatomical_structure
Gestational diabetes-mellitus
Peptide
Systolic blood pressure
Intercellular Signaling Peptides and Proteins
Female
Human
Adult
medicine.medical_specialty
Cord
Clinical article
Birth weight
Maternal blood
Case control study
Diastole
Adropin
Severity
Article
Preeclampsia
Young Adult
03 medical and health sciences
Diastolic blood pressure
Internal medicine
Thrombocyte count
medicine
Humans
In patient
Disease severity
Obstetric delivery
Enho protein, human
business.industry
Endothelial function
medicine.disease
Severe preeclampsia
Plasma protein
Biological marker
030104 developmental biology
Endocrinology
Perinatal period
Dysfunction
Blood Level
Peptide Hormones
Amylin
Case-Control Studies
Pediatrics, Perinatology and Child Health
Blood level
Prediction
Peptides
business
Controlled study
Biomarkers
- Language
- ISSN
- 1619-3997
0300-5577
Aim: To investigate both maternal and umbilical cord adropin levels in patients with preeclampsia and the possible relations with its severity and perinatal outcomes. Materials and methods: In this study, a total of 38 preeclamptic and 40 age-matched healthy pregnant women between January and June 2016 were included. Serum and cord adropin levels were measured using an enzyme-linked immunosorbent assay (ELISA). Results: The maternal and umbilical cord adropin levels were significantly lower in the preeclamptic group compared to controls [71.19±22.21 vs. 100.76±27.02 ng/L and 92.39 (59.77:129.89) vs. 106.20 (74.42:208.02) ng/L, P Conclusion: The present study is the first to demonstrate a significant association between maternal and umbilical adropin levels and the presence and severity of preeclampsia. Adropin might be a useful parameter for predicting the presence and severity of preeclampsia.