Semi-Continuous Cultures as a Tool for Cell Line Characterization During Process Development
- Resource Type
- Authors
- J. Palacio; Adolfo Castillo; L. Rojas; Y. Rabasa; Svieta Victores; A. Figueredo; E. Faife; Y. Alvarez
- Source
- Cells and Culture ISBN: 9789048134182
- Subject
- Computer science
Process development
Growth phase
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Biochemical engineering
Simplicity
Characterization (materials science)
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- Language
Although continuous cultures (CC) studies has been recognized as the standard method for cell line characterization, thorough and precise studies makes its use prohibitively costly. Batch cultures have also been used for this purpose due to its simplicity, but because of the constantly changing environment results obtained are reliable only for non limited growth phase.