ZJ0273, propyl 424,6dimethoxypyrimidin2yloxybenzylaminobenzoate, is a broadspectrum herbicidal ingredient used for weed control in oilseed rape in China. Two monolabeled ZJ0273, propyl 424,6dimethoxypyrimidin2yloxyphenyl3,4,5,63H4benzylaminobenzoate 7 and propyl 424,6dimethoxy4,614C2pyrimidin2yloxybenzylaminobenzoate 12, were synthesized separately from 2,3,4,5,63H5phenol in a fourstep yield of 27 and from 4,6dichloro2methylthio4,614C2pyrimidine in a threestep yield of 54. In addition, two duallabeled analogues of ZJ0273 were prepared by homogeneously mixing tritiumlabeled ZJ0273 7 in the benzyl ring separately with two carbon14labeled ZJ0273 2, 12 in the benzoate ring and the pyrimidine ring. These labeled ZJ0273 could be used as radiotracers in the studies on the metabolism, mode of action, environmental behavior, and fate of ZJ0273. Copyright © 2008 John Wiley & Sons, Ltd.